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The term "endocrine" implies secretion into the internal milieu of a multicellular organism In contrast to exocrine tissues, where the secretory products are discharged into the external space the outer surface of the body, mucosal surfaces, duct systems the endocrine organs and cells secrete their products into the vascular systemFig 1 Pancreas, Human, (H & E) IL, Islets of Langerhans Examine a sample of pancreatic tissue with the 4X objective and identify the exocrine and endocrine portions of the pancreas The endocrine portion of the pancreas consists of islands of endocrine cells called the Islets of Langerhans (IL) The number of islets present in your sectionThe pancreas is a long, slender organ, most of which is located posterior to the bottom half of the stomach (Figure 1791)Although it is primarily an exocrine gland, secreting a variety of digestive enzymes, the pancreas also has endocrine cells Its pancreatic islets—clusters of cells formerly known as the islets